Apnea of Prematurity is linked

Potentially life-threatening breathing pauses in the challenge, characterised by that last longer than 20 seconds, apnea prematurity (PDO) affects more than 50% of premature infants and is almost universal in the smallest preemies. Partly due to the underdeveloped spinal cannot adequately regulate breathing while outside of, in particular during the sleep, the PDO is not yet fully not understood by scientists and remains a serious concern among neonatologists and parents.

New research published in the October edition of the University of Massachusetts and the Medical School that heredity may play in the determination of infant susceptibility to PDO strong role and may lead to the development of more effective treatment and screening methods of clinical scientists.

Elisabeth b. Salisbury, PhD, Professor of Neurology, David Paydarfar, MD, Professor of Neurology and Physiology at the University of Massachusetts Medical School and colleagues compared the rates of PDO 217 pairs of the same pair, the brethren, and to determine whether the inheritance played a role in the condition. Using advanced statistical models, the calculation of the correlation in the twins born to establish a PDO before 36 weeks gestational age to determine whether the components are responsible. To discover that, in the cases of the twin of the same sex, where one of the brethren OF THE PDO, the other pair has had 62% probability of a pair with PDO. In identical twins, was significantly higher correlation between two PDO diagnostic identical pairs-87%.

These findings indicate that genetic influences shared by identical twins have played a significant part in the development of PDO. "While the actors, including the environment, to contribute to PDO, our study suggests that the surprisingly strong genetic predispozice for PDO. Further research is needed to confirm our results and find a gene or group of genes that are linked to this common respiratory disorders, "said Paydarfar.

flagged: PDO ‧ PDO Diagnostics ‧ Apnea apnea of prematurity ‧ ‧ genetics ‧ pause breathing

Below: Clinical research ‧ obstructive sleep Apnea sleep Apnea

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