5-HTP is a naturally derived amino acid that has been shown in comprehensive studies to be safer than prescription drugs for the treatment of insomnia and depression, and can also be used for treating obesity, migraine headaches, fibromyalgia, and premenstrual syndrome. It may prove to be more popular than St. John's wort for the treatment of depression and other serotonin-related conditions, as it's been shown to produce results in as little as two weeks, while the herb may take a month or longer. Author Michael Murray, N.D., a leading naturopath and coauthor of The Encyclopedia of Natural Medicine, delves very deeply to explain the hows and whys of depression at the neurotransmitter level, and the illustrations of presynaptic membranes may be a bit much for the lay reader. There are also several sections with intimidating titles along the lines of "Enhancing 5-HTP with Catecholamine Precursors." But the book's comprehensiveness makes up for its occasional denseness. Murray includes enlightening sections on nutrition for peak serotonin synthesis, other complementary herbal supplements, and many online and physical sources for obtaining 5-HTP. --Erica Jorgensen
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